About Us

What is a checkpoint and what are we aiming for?

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Young Investigator Retreat 2024: December 11th

A retreat by and for our Young Investigators to network and exchange idea’s.

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Projects

Check out our research projects dealing with immunological, glial and neuronal checkpoints of CNS recovery.

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Teaching Series

Learn about the Checkpoints of CNS Recovery with our experts during this lecture series

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TRR 274 Retreat: December 12th & 13th

Join us at the 2024 Retreat at the Alte Mensa in Göttingen

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Our Vision

The central nervous system (CNS) is a terminally differentiated tissue, that can endure injury through many different avenues. The tissue response to such an insult is variable and can range from irreversible destruction to almost complete recovery. The rules that govern these divergent outcomes are still unknown.

Our team of researchers from Munich and Göttingen, ranging from immunologists, neurobiologists to glial biologists, has come together to establish this transregional collaborative research centre to understand and study the biology of the multi-cellular response that determines recovery after CNS injury. 

Our aim is to define the immunological, glial and neuronal checkpoints that faithfully predict the outcome of CNS injuries, and to develop intervention strategies targeting these checkpoints that guide an injured CNS tissue towards recovery.

We strive to uncover and understand the crucial steps, or checkpoints, within the immunological, glial and neuronal response to CNS injury that will ultimately lead to its recovery and repair.
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News

  • 22. October 2024
    APOE aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis
  • 14. October 2024
    Magdalena Götz Awarded the Bavarian Order of Merit
  • 5. October 2024
    Network of German Neurocenters @ SfN 2024
  • 27. September 2024
    CD8+ T cells drive inflammation in both prodromal and established MS
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Events

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